5V62: Phospho-ERK2 bound to bivalent inhibitor SBP3

PDB ID: 5V62Download
MMDB ID: 153050
PDB Deposition Date: 2017/3/15
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 5V62: dimeric; determined by author and by software (PISA)
Molecular Components in 5V62
Label Count Molecule
Proteins (2 molecules)
1
Mitogen-activated Protein Kinase 1
(Gene symbol: MAPK1)
Molecule annotation
1
Ribosomal Protein S6 Kinase Alpha-1
(Gene symbol: RPS6KA1)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
5
GLYCEROLGLYCEROL
2
1
5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE
3
1
N-(hex-5-yn-1-yl)hexanamideN-(hex-5-yn-1-yl)hexanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303