5V57: 3.0A SYN structure of the multi-domain human smoothened receptor in complex with TC114

PDB ID: 5V57Download
MMDB ID: 151150
PDB Deposition Date: 2017/3/13
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 3  Å
Source Organism:
Similar Structures:
Biological Unit for 5V57: dimeric; determined by author
Molecular Components in 5V57
Label Count Molecule
Proteins (2 molecules)
2
Smoothened Homolog,flavodoxin,smoothened Homolog
(Gene symbol: DVU2680)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
N-methyl-N-[1-[4-(2-methylpyrazol-3-yl)phthalazin-1-yl]piperidin-4-yl]-4-nitro-2-(trifluoromethyl)benzamideN-methyl-N-[1-[4-(2-methylpyrazol-3-yl)phthalazin-1-yl]piperidin-4-yl]-4-nitro-2-(trifluoromethyl)benzamide
2
2
FLAVIN MONONUCLEOTIDEFLAVIN MONONUCLEOTIDE
3
1
(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303