5V4W: Human glucokinase in complex with novel indazole activator

PDB ID: 5V4WDownload
MMDB ID: 151390
PDB Deposition Date: 2017/3/10
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 2.39  Å
Source Organism:
Similar Structures:
Biological Unit for 5V4W: monomeric; determined by author and by software (PISA)
Molecular Components in 5V4W
Label Count Molecule
Protein (1 molecule)
1
Glucokinase
(Gene symbol: GCK)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
alpha-D-glucopyranosealpha-D-glucopyranose
2
1
(2S)-2-[4-(cyclopropylsulfonyl)-1H-indazol-1-yl]-N-(5-fluoro-1,3-thiazol-2-yl)-3-(oxan-4-yl)propanamide(2S)-2-[4-(cyclopropylsulfonyl)-1H-indazol-1-yl]-N-(5-fluoro-1,3-thiazol-2-yl)-3-(oxan-4-yl)propanamide
3
1
IODIDE IONIODIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303