5V3O: Cereblon in complex with DDB1 and CC-220

PDB ID: 5V3ODownload
MMDB ID: 150524
PDB Deposition Date: 2017/3/7
Updated in MMDB: 2017/05
Experimental Method:
x-ray diffraction
Resolution: 3.2  Å
Source Organism:
Similar Structures:
Biological Unit for 5V3O: dimeric; determined by author and by software (PISA)
Molecular Components in 5V3O
Label Count Molecule
Proteins (2 molecules)
1
DNA Damage-binding Protein 1
(Gene symbol: DDB1)
Molecule annotation
1
Protein Cereblon
(Gene symbol: CRBN)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
(3S)-3-[4-({4-[(morpholin-4-yl)methyl]phenyl}methoxy)-1-oxo-1,3-dihydro-2H-isoindol-2-yl]piperidine-2,6-dione(3S)-3-[4-({4-[(morpholin-4-yl)methyl]phenyl}methoxy)-1-oxo-1,3-dihydro-2H-isoindol-2-yl]piperidine-2,6-dione
2
1
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303