5V22: Crystal structure of human SETD2 SET-domain in complex with H3K36M peptide and SAH

PDB ID: 5V22Download
MMDB ID: 148967
PDB Deposition Date: 2017/3/2
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 5V22: dimeric; determined by author and by software (PISA)
Molecular Components in 5V22
Label Count Molecule
Proteins (2 molecules)
1
Histone-lysine N-methyltransferase Setd2
(Gene symbol: SETD2)
Molecule annotation
1
Histone H3k36m Peptide
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
3
ZINC IONZINC ION
2
1
S-ADENOSYL-L-HOMOCYSTEINES-ADENOSYL-L-HOMOCYSTEINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303