5UT0: JAK2 JH2 in complex with AT9283

PDB ID: 5UT0Download
MMDB ID: 151592
PDB Deposition Date: 2017/2/14
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.102  Å
Source Organism:
Similar Structures:
Biological Unit for 5UT0: monomeric; determined by author
Molecular Components in 5UT0
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase Jak2
(Gene symbol: JAK2)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
GLYCEROLGLYCEROL
2
1
1-cyclopropyl-3-{3-[5-(morpholin-4-ylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl}urea1-cyclopropyl-3-{3-[5-(morpholin-4-ylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl}urea
3
1
ACETATE IONACETATE ION
4
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303