5UR1: FGFR1 kinase domain complex with SN37333 in reversible binding mode

PDB ID: 5UR1Download
MMDB ID: 151380
PDB Deposition Date: 2017/2/9
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 5UR1: monomeric; determined by author and by software (PISA)
Molecular Components in 5UR1
Label Count Molecule
Protein (1 molecule)
1
Fibroblast Growth Factor Receptor 1
(Gene symbol: FGFR1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-{1-[4-(dimethylamino)but-2-enoyl]piperidin-4-yl}-7-(phenylamino)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-{1-[4-(dimethylamino)but-2-enoyl]piperidin-4-yl}-7-(phenylamino)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303