5UPE: Crystal structure of human NAMPT with isoindoline urea inhibitor compound 5

PDB ID: 5UPEDownload
MMDB ID: 152253
PDB Deposition Date: 2017/2/2
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 1.93  Å
Source Organism:
Similar Structures:
Biological Unit for 5UPE: dimeric; determined by author and by software (PISA)
Molecular Components in 5UPE
Label Count Molecule
Proteins (2 molecules)
2
Nicotinamide Phosphoribosyltransferase
(Gene symbol: NAMPT)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
N-{4-[(3-phenylpropyl)carbamoyl]phenyl}-2H-isoindole-2-carboxamideN-{4-[(3-phenylpropyl)carbamoyl]phenyl}-2H-isoindole-2-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303