5UOQ: CRYSTAL STRUCTURE OF THE PROTOTYPE FOAMY VIRUS INTASOME WITH A 2- PYRIDINONE AMINAL INHIBITOR (COMPOUND 31)

PDB ID: 5UOQDownload
MMDB ID: 149397
PDB Deposition Date: 2017/2/1
Updated in MMDB: 2017/04
Experimental Method:
x-ray diffraction
Resolution: 2.61  Å
Source Organism:
Similar Structures:
Biological Unit for 5UOQ: octameric; determined by author and by software (PISA)
Molecular Components in 5UOQ
Label Count Molecule
Proteins (4 molecules)
4
Integrase
Molecule annotation
Nucleotides(4 molecules)
2
Nucleotide Preprocessed PFV Donor DNA (Non-transferred Strand)
Molecule annotation
2
Nucleotide Preprocessed PFV Donor DNA (Transferred Strand)
Molecule annotation
Chemicals and Non-standard biopolymers (26 molecules)
1
2
ZINC IONZINC ION
2
10
GLYCEROLGLYCEROL
3
6
MAGNESIUM IONMAGNESIUM ION
4
6
SULFATE IONSULFATE ION
5
2
(3R)-8-[(3-chloro-4-fluorophenyl)methyl]-6-hydroxy-1,5,7-trioxo-1,2',3',5,7,8,9,10-octahydro-2H-spiro[imidazo[5,1-a][2,6]naphthyridine-3,1'-indene]-7'-carbonitrile(3R)-8-[(3-chloro-4-fluorophenyl)methyl]-6-hydroxy-1,5,7-trioxo-1,2',3',5,7,8,9,10-octahydro-2H-spiro[imidazo[5,1-a][2,6]naphthyridine-3,1'-indene]-7'-carbonitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303