5UJF: Crystal Structure of Mycobacterium tuberculosis Dihydrofolate Reductase Bound p218 Inhibitor

PDB ID: 5UJFDownload
MMDB ID: 147067
PDB Deposition Date: 2017/1/17
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 5UJF: monomeric; determined by author
Molecular Components in 5UJF
Label Count Molecule
Protein (1 molecule)
1
Dihydrofolate Reductase
(Gene symbol: dfrA)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
3
SULFATE IONSULFATE ION
2
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
1
3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303