5UJ2: Crystal structure of HCV NS5B genotype 2A JFH-1 isolate with S15G E86Q E87Q C223H V321I mutations and Delta8 neta hairpoin loop deletion in complex with GS-639476 (diphsohate version of GS-9813), Mn2+ and symmetrical primer template 5'-AUAAAUUU

PDB ID: 5UJ2Download
MMDB ID: 148933
PDB Deposition Date: 2017/1/16
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.9  Å
Source Organism:
Hepacivirus hominis▼
Similar Structures:
Biological Unit for 5UJ2: trimeric; determined by author and by software (PISA)
Molecular Components in 5UJ2
Label Count Molecule
Protein (1 molecule)
1
Genome Polyprotein
Molecule annotation
Nucleotides(2 molecules)
2
RNA (5'-r(*ap*up*ap*ap*ap*up*up*u)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
3
MANGANESE (II) IONMANGANESE (II) ION
2
1
(1S)-1-(4-aminoimidazo[2,1-f][1,2,4]triazin-7-yl)-1,4-anhydro-2-deoxy-2-fluoro-5-O-[(S)-hydroxy(phosphonooxy)phosphoryl]-2-methyl-D-ribitol(1S)-1-(4-aminoimidazo[2,1-f][1,2,4]triazin-7-yl)-1,4-anhydro-2-deoxy-2-fluoro-5-O-[(S)-hydroxy(phosphonooxy)phosphoryl]-2-methyl-D-ribitol
3
1
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303