5UIG: Crystal structure of adenosine A2A receptor bound to a novel triazole-carboximidamide antagonist

PDB ID: 5UIGDownload
MMDB ID: 147211
PDB Deposition Date: 2017/1/13
Updated in MMDB: 2018/11
Experimental Method:
x-ray diffraction
Resolution: 3.5  Å
Source Organism:
Similar Structures:
Biological Unit for 5UIG: monomeric; determined by author
Molecular Components in 5UIG
Label Count Molecule
Protein (1 molecule)
1
Adenosine Receptor A2a,soluble Cytochrome B562,adenosine Receptor A2A
(Gene symbol: ADORA2A)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
{[-(BIS-CARBOXYMETHYL-AMINO)-ETHYL]-CARBOXYMETHYL-AMINO}-ACETIC ACID{[-(BIS-CARBOXYMETHYL-AMINO)-ETHYL]-CARBOXYMETHYL-AMINO}-ACETIC ACID
2
1
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
3
1
5-amino-N-[(2-methoxyphenyl)methyl]-2-(3-methylphenyl)-2H-1,2,3-triazole-4-carboximidamide5-amino-N-[(2-methoxyphenyl)methyl]-2-(3-methylphenyl)-2H-1,2,3-triazole-4-carboximidamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303