5UHB: Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with Rifampin

PDB ID: 5UHBDownload
MMDB ID: 149776
PDB Deposition Date: 2017/1/11
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 4.29  Å
Source Organism:
Mycobacterium tuberculosis H37Rv▼
Similar Structures:
Biological Unit for 5UHB: octameric; determined by author and by software (PISA)
Molecular Components in 5UHB
Label Count Molecule
Proteins (6 molecules)
2
DNA-directed RNA Polymerase Subunit Alpha
Molecule annotation
1
DNA-directed RNA Polymerase Subunit Beta
Molecule annotation
1
DNA-directed RNA Polymerase Subunit Beta'
Molecule annotation
1
DNA-directed RNA Polymerase Subunit Omega
Molecule annotation
1
RNA Polymerase Sigma Factor Siga
Molecule annotation
Nucleotides(2 molecules)
1
DNA (5'-d(*tp*ap*tp*ap*ap*tp*gp*gp*gp*ap*gp*cp*tp*gp*tp*cp*ap*cp*gp*gp*ap*tp*g)-3')
Molecule annotation
1
DNA (5'-d(*cp*ap*tp*cp*cp*gp*tp*gp*ap*gp*tp*cp*gp*ap*gp*g)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
RIFAMPICINRIFAMPICIN
2
2
ZINC IONZINC ION
3
1
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303