5UGH: Crystal structure of Mat2a bound to the allosteric inhibitor PF-02929366

PDB ID: 5UGHDownload
MMDB ID: 150875
PDB Deposition Date: 2017/1/8
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.062  Å
Source Organism:
Similar Structures:
Biological Unit for 5UGH: dimeric; determined by author and by software (PISA)
Molecular Components in 5UGH
Label Count Molecule
Proteins (2 molecules)
2
S-adenosylmethionine Synthase Isoform Type-2
(Gene symbol: MAT2A)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
2-(7-chloro-5-phenyl[1,2,4]triazolo[4,3-a]quinolin-1-yl)-N,N-dimethylethan-1-amine2-(7-chloro-5-phenyl[1,2,4]triazolo[4,3-a]quinolin-1-yl)-N,N-dimethylethan-1-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303