5U6J: Factor VIIa in complex with the inhibitor 3-{[(2R)-17-ethyl-4-methyl-3,12-dioxo-7-[(propan-2-yl)sulfonyl]-13-oxa-4,11-diazatricyclo[14.2.2.1~6,10~]henicosa-1(18),6(21),7,9,16,19-hexaen-2-yl]amino}benzamide

PDB ID: 5U6JDownload
MMDB ID: 150698
PDB Deposition Date: 2016/12/8
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 5U6J: dimeric; determined by author and by software (PISA)
Molecular Components in 5U6J
Label Count Molecule
Proteins (2 molecules)
1
Coagulation Factor VII Heavy Chain
(Gene symbol: F7)
Molecule annotation
1
Coagulation Factor VII Light Chain
(Gene symbol: F7)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
1
3-{[(2R)-17-ethyl-4-methyl-3,12-dioxo-7-[(propan-2-yl)sulfonyl]-13-oxa-4,11-diazatricyclo[14.2.2.1~6,10~]henicosa-1(18),6(21),7,9,16,19-hexaen-2-yl]amino}benzamide3-{[(2R)-17-ethyl-4-methyl-3,12-dioxo-7-[(propan-2-yl)sulfonyl]-13-oxa-4,11-diazatricyclo[14.2.2.1~6,10~]henicosa-1(18),6(21),7,9,16,19-hexaen-2-yl]amino}benzamide
2
1
CALCIUM IONCALCIUM ION
3
4
SULFATE IONSULFATE ION
4
2
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303