5U6B: Structure of the Axl kinase domain in complex with a macrocyclic inhibitor

PDB ID: 5U6BDownload
MMDB ID: 153024
PDB Deposition Date: 2016/12/7
Updated in MMDB: 2017/10
Experimental Method:
x-ray diffraction
Resolution: 2.84  Å
Source Organism:
Similar Structures:
Biological Unit for 5U6B: monomeric; determined by author and by software (PISA)
Molecular Components in 5U6B
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase Receptor UFO
(Gene symbol: AXL)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(10R)-7-amino-11-chloro-12-fluoro-1-(2-hydroxyethyl)-3,10,16-trimethyl-16,17-dihydro-1H-8,4-(azeno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecin-15(10H)-one(10R)-7-amino-11-chloro-12-fluoro-1-(2-hydroxyethyl)-3,10,16-trimethyl-16,17-dihydro-1H-8,4-(azeno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecin-15(10H)-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303