5U2H: Crystal structure of the ATP-gated P2X7 ion channel bound to ATP and allosteric antagonist A804598

PDB ID: 5U2HDownload
MMDB ID: 146139
PDB Deposition Date: 2016/11/30
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 3.903  Å
Source Organism:
Similar Structures:
Biological Unit for 5U2H: trimeric; determined by author and by software (PISA)
Molecular Components in 5U2H
Label Count Molecule
Proteins (3 molecules)
3
P2X Purinoceptor
(Gene symbol: P2RX7)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
5
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
3
N-cyano-N'-[(1R)-1-phenylethyl]-N''-quinolin-5-ylguanidineN-cyano-N'-[(1R)-1-phenylethyl]-N''-quinolin-5-ylguanidine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303