5TXO: STRUCTURE OF Q151M complex (A62V, V75I, F77L, F116Y, Q151M) mutant HIV-1 REVERSE TRANSCRIPTASE (RT) TERNARY COMPLEX WITH A DOUBLE STRANDED DNA AND AN INCOMING DATP

PDB ID: 5TXODownload
MMDB ID: 149571
PDB Deposition Date: 2016/11/17
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 2.546  Å
Source Organism:
Human immunodeficiency virus type 1 BH10▼
Similar Structures:
Biological Unit for 5TXO: tetrameric; determined by author and by software (PISA)
Molecular Components in 5TXO
Label Count Molecule
Proteins (2 molecules)
1
Hiv-1 Reverse Transcriptase P66 Subunit
Molecule annotation
1
Hiv-1 Reverse Transcriptase P51 Subunit
Molecule annotation
Nucleotides(2 molecules)
1
DNA (5'-d(*tp*gp*gp*tp*cp*gp*gp*cp*gp*cp*cp*cp*gp*ap*ap*cp*ap*gp*gp*gp*ap*cp*tp*g)-3')
Molecule annotation
1
DNA (5'-d(*cp*ap*gp*tp*cp*cp*cp*tp*gp*tp*tp*cp*gp*gp*(mrg)p*cp*gp*cp*cp*g)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
2
alpha-D-glucopyranosealpha-D-glucopyranose
2
2
beta-D-fructofuranosebeta-D-fructofuranose
3
2
MAGNESIUM IONMAGNESIUM ION
4
1
2'-DEOXYADENOSINE 5'-TRIPHOSPHATE2'-DEOXYADENOSINE 5'-TRIPHOSPHATE
5
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
6
1
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303