5TWM: CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS GENOTYPE 2A STRAIN JFH1 L30S NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 5-[3-(tert-butylcarbamoyl)phenyl]-6-(ethylamino)-2-(4-fluorophenyl)-N-methylfuro[2,3-b]pyridine-3-carboxamide

PDB ID: 5TWMDownload
MMDB ID: 148429
PDB Deposition Date: 2016/11/14
Updated in MMDB: 2018/11
Experimental Method:
x-ray diffraction
Resolution: 1.97  Å
Source Organism:
Similar Structures:
Biological Unit for 5TWM: monomeric; determined by author
Molecular Components in 5TWM
Label Count Molecule
Protein (1 molecule)
1
Ns5b RNA-dependent RNA Polymerase
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
1
5-[3-(tert-butylcarbamoyl)phenyl]-6-(ethylamino)-2-(4-fluorophenyl)-N-methylfuro[2,3-b]pyridine-3-carboxamide5-[3-(tert-butylcarbamoyl)phenyl]-6-(ethylamino)-2-(4-fluorophenyl)-N-methylfuro[2,3-b]pyridine-3-carboxamide
2
4
SULFATE IONSULFATE ION
3
1
3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL
4
2
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303