5TVJ: Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with CoA and inhibitor 2k*: 1-(4-fluorophenyl)-2-[2-(4-methylphenyl)-2-oxoethyl]pyrrolo[1,2-a]pyrazin-2-ium

PDB ID: 5TVJDownload
MMDB ID: 147781
PDB Deposition Date: 2016/11/9
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 5TVJ: hexameric; determined by author and by software (PISA)
Molecular Components in 5TVJ
Label Count Molecule
Proteins (6 molecules)
6
Enhanced Intracellular Survival Protein
(Gene symbol: eis)
Molecule annotation
Chemicals and Non-standard biopolymers (24 molecules)
1
6
COENZYME ACOENZYME A
2
6
1-(4-fluorophenyl)-2-[2-(4-methylphenyl)-2-oxoethyl]pyrrolo[1,2-a]pyrazin-2-ium1-(4-fluorophenyl)-2-[2-(4-methylphenyl)-2-oxoethyl]pyrrolo[1,2-a]pyrazin-2-ium
3
6
GLYCEROLGLYCEROL
4
6
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303