5TVF: Crystal structure of Trypanosoma brucei AdoMetDC/prozyme heterodimer in complex with inhibitor CGP 40215

PDB ID: 5TVFDownload
MMDB ID: 146375
PDB Deposition Date: 2016/11/8
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 2.42  Å
Source Organism:
Similar Structures:
Biological Unit for 5TVF: trimeric; determined by author and by software (PISA)
Molecular Components in 5TVF
Label Count Molecule
Proteins (3 molecules)
1
S-adenosylmethionine Decarboxylase Beta Chain
(Gene symbol: Tb927.6.4410)
Molecule annotation
1
S-adenosylmethionine Decarboxylase Alpha Chain
(Gene symbol: Tb927.6.4410)
Molecule annotation
1
S-adenosylmethionine Decarboxylase Proenzyme-like, Putative
(Gene symbol: Tb927.6.4470)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
2
1
3-[C-[N'-(3-CARBAMIMIDOYL-BENZYLIDENIUM)-HYDRAZINO]-[[AMINOMETHYLIDENE]AMINIUM]-IMINOMETHYL]-BENZAMIDINIUM3-[C-[N'-(3-CARBAMIMIDOYL-BENZYLIDENIUM)-HYDRAZINO]-[[AMINOMETHYLIDENE]AMINIUM]-IMINOMETHYL]-BENZAMIDINIUM
3
2
1,4-DIAMINOBUTANE1,4-DIAMINOBUTANE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303