5TVC: Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 3 nicotinic acetylcholine receptor in complex with (E,2S)-N-methyl-5-(5-phenoxy-3-pyridyl)pent-4-en-2-amine (TI-5312)

PDB ID: 5TVCDownload
MMDB ID: 145323
PDB Deposition Date: 2016/11/8
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 1.926  Å
Source Organism:
Similar Structures:
Biological Unit for 5TVC: pentameric; determined by author and by software (PISA)
Molecular Components in 5TVC
Label Count Molecule
Proteins (5 molecules)
5
Soluble Acetylcholine Receptor,neuronal Acetylcholine Receptor Subunit Alpha-3 Chimera
(Gene symbol: CHRNA3)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
6
SULFATE IONSULFATE ION
2
1
PENTAETHYLENE GLYCOLPENTAETHYLENE GLYCOL
3
4
(E,2S)-N-methyl-5-(5-phenoxy-3-pyridyl)pent-4-en-2-amine(E,2S)-N-methyl-5-(5-phenoxy-3-pyridyl)pent-4-en-2-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303