5TOL: Crystal Structure Of Beta-site App-cleaving Enzyme 1 Complexed With N- (3-((4as,7as)-2-amino-4,4a,5,6-tetrahydro-7ah-furo[2,3-d][1, 3]thiazin-7a-yl)-4-fluorophenyl)-5-bromo-2-pyridinecarboxamide

PDB ID: 5TOLDownload
MMDB ID: 145186
PDB Deposition Date: 2016/10/18
Updated in MMDB: 2016/12
Experimental Method:
x-ray diffraction
Resolution: 2.51  Å
Source Organism:
Similar Structures:
Biological Unit for 5TOL: monomeric; determined by author and by software (PISA)
Molecular Components in 5TOL
Label Count Molecule
Protein (1 molecule)
1
Beta-secretase 1
(Gene symbol: BACE1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-{3-[(4ar,7ar)-2-Amino-4,4a,5,6-Tetrahydro-7ah-Furo[2,3-D][1,3]thiazin-7a-Yl]-4-Fluorophenyl}-5-Bromopyridine-2-CarboxamideN-{3-[(4ar,7ar)-2-Amino-4,4a,5,6-Tetrahydro-7ah-Furo[2,3-D][1,3]thiazin-7a-Yl]-4-Fluorophenyl}-5-Bromopyridine-2-Carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303