5TO3: Crystal structure of thrombin mutant W215A/E217A fused to EGF456 of thrombomodulin via a 31-residue linker and bound to PPACK

PDB ID: 5TO3Download
MMDB ID: 149372
PDB Deposition Date: 2016/10/16
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 2.34  Å
Source Organism:
Similar Structures:
Biological Unit for 5TO3: dimeric; determined by author and by software (PISA)
Molecular Components in 5TO3
Label Count Molecule
Proteins (2 molecules)
1
Prothrombin
(Gene symbol: F2)
Molecule annotation
1
Prothrombin,thrombomodulin
(Gene symbol: F2)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
4
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
4
beta-D-mannopyranosebeta-D-mannopyranose
3
1
alpha-D-mannopyranosealpha-D-mannopyranose
4
1
D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamideD-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide
5
1
POTASSIUM IONPOTASSIUM ION
6
1
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303