5TN8: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with (E)-4'-hydroxy-3-((hydroxyiminio)methyl)-[1,1'-biphenyl]-4-olate

PDB ID: 5TN8Download
MMDB ID: 146654
PDB Deposition Date: 2016/10/13
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 2.652  Å
Source Organism:
Similar Structures:
Biological Unit for 5TN8: tetrameric; determined by author and by software (PISA)
Molecular Components in 5TN8
Label Count Molecule
Proteins (4 molecules)
2
Estrogen Receptor
(Gene symbol: ESR1)
Molecule annotation
2
Nuclear Receptor Coactivator 2
(Gene symbol: NCOA2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
3-[(Z)-(hydroxyimino)methyl][1,1'-biphenyl]-4,4'-diol3-[(Z)-(hydroxyimino)methyl][1,1'-biphenyl]-4,4'-diol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303