5TLX: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with 3,4-bis(4-hydroxyphenyl)thiophene 1,1-dioxide

PDB ID: 5TLXDownload
MMDB ID: 146626
PDB Deposition Date: 2016/10/12
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 2.103  Å
Source Organism:
Similar Structures:
Biological Unit for 5TLX: tetrameric; determined by author and by software (PISA)
Molecular Components in 5TLX
Label Count Molecule
Proteins (4 molecules)
2
Estrogen Receptor
(Gene symbol: ESR1)
Molecule annotation
2
Nuclear Receptor Coactivator 2
(Gene symbol: NCOA2)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
3-methyl-6-phenyl-3H-imidazo[4,5-b]pyridin-2-amine3-methyl-6-phenyl-3H-imidazo[4,5-b]pyridin-2-amine
2
4
3,4-bis(4-hydroxyphenyl)-2,5-dihydro-1H-1lambda~6~-thiophene-1,1-dione3,4-bis(4-hydroxyphenyl)-2,5-dihydro-1H-1lambda~6~-thiophene-1,1-dione
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303