5TLU: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the PEG-linked Dimeric Estrogen, EE2-(eg)6-EE2-amine

PDB ID: 5TLUDownload
MMDB ID: 146624
PDB Deposition Date: 2016/10/12
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 2.223  Å
Source Organism:
Similar Structures:
Biological Unit for 5TLU: tetrameric; determined by author and by software (PISA)
Molecular Components in 5TLU
Label Count Molecule
Proteins (4 molecules)
2
Estrogen Receptor
(Gene symbol: ESR1)
Molecule annotation
2
Nuclear Receptor Coactivator 2
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
(14beta,17alpha)-21-(4-aminophenyl)-19-norpregna-1(10),2,4-trien-20-yne-3,17-diol(14beta,17alpha)-21-(4-aminophenyl)-19-norpregna-1(10),2,4-trien-20-yne-3,17-diol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303