5TL9: crystal structure of mPGES-1 bound to inhibitor

PDB ID: 5TL9Download
MMDB ID: 147774
PDB Deposition Date: 2016/10/10
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.2  Å
Source Organism:
Similar Structures:
Biological Unit for 5TL9: trimeric; determined by author and by software (PISA)
Molecular Components in 5TL9
Label Count Molecule
Proteins (3 molecules)
3
Prostaglandin E Synthase
(Gene symbol: PTGES)
Molecule annotation
Chemicals and Non-standard biopolymers (21 molecules)
1
3
2-{2-[(1S,2S)-2-{[1-(8-methylquinolin-2-yl)piperidine-4-carbonyl]amino}cyclopentyl]ethyl}benzoic acid2-{2-[(1S,2S)-2-{[1-(8-methylquinolin-2-yl)piperidine-4-carbonyl]amino}cyclopentyl]ethyl}benzoic acid
2
3
GLUTATHIONEGLUTATHIONE
3
3
hexyl beta-D-glucopyranosidehexyl beta-D-glucopyranoside
4
3
octyl beta-D-glucopyranosideoctyl beta-D-glucopyranoside
5
6
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
6
3
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303