5THS: Crystal Structure of G302A HDAC8 in complex with M344

PDB ID: 5THSDownload
MMDB ID: 145885
PDB Deposition Date: 2016/9/30
Updated in MMDB: 2016/12
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 5THS: monomeric; determined by author and by software (PISA)
Molecular Components in 5THS
Label Count Molecule
Protein (1 molecule)
1
Histone Deacetylase 8
(Gene symbol: HDAC8)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
1
ZINC IONZINC ION
2
2
POTASSIUM IONPOTASSIUM ION
3
2
4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
4
7
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303