5THO: Crystal Structure of Mycobacterium Tuberculosis Proteasome in complex with N,C-capped Dipeptide Inhibitor PKS2205

PDB ID: 5THODownload
MMDB ID: 146357
PDB Deposition Date: 2016/9/30
Updated in MMDB: 2022/11
Experimental Method:
x-ray diffraction
Resolution: 3.002  Å
Source Organism:
Similar Structures:
Biological Unit for 5THO: 28-meric; determined by author and by software (PISA)
Molecular Components in 5THO
Label Count Molecule
Proteins (28 molecules)
14
Proteasome Subunit Alpha
Molecule annotation
14
Proteasome Subunit Beta
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
14
N,N-diethyl-N~2~-(3-phenylpropanoyl)-L-asparaginyl-O-methyl-N-[(naphthalen-1-yl)methyl]-L-serinamideN,N-diethyl-N~2~-(3-phenylpropanoyl)-L-asparaginyl-O-methyl-N-[(naphthalen-1-yl)methyl]-L-serinamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303