5TH9: Structure determination of a potent, selective antibody inhibitor of human MMP9 (GS-5745 bound to MMP-9)

PDB ID: 5TH9Download
MMDB ID: 148422
PDB Deposition Date: 2016/9/29
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.999  Å
Source Organism:
Oryctolagus cuniculus▼
Similar Structures:
Biological Unit for 5TH9: trimeric; determined by author and by software (PISA)
Molecular Components in 5TH9
Label Count Molecule
Proteins (3 molecules)
1
Gs-5745 FAB Light Chain
Molecule annotation
1
Gs-5745 FAB Heavy Chain
Molecule annotation
1
Matrix Metalloproteinase-9,matrix Metalloproteinase-9
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
ZINC IONZINC ION
2
2
CALCIUM IONCALCIUM ION
3
1
COBALT HEXAMMINE(III)COBALT HEXAMMINE(III)
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303