5TCI: Crystal structure of tryptophan synthase from M. tuberculosis - BRD4592-bound form

PDB ID: 5TCIDownload
MMDB ID: 151345
PDB Deposition Date: 2016/9/15
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.45  Å
Source Organism:
Similar Structures:
Biological Unit for 5TCI: tetrameric; determined by author and by software (PISA)
Molecular Components in 5TCI
Label Count Molecule
Proteins (4 molecules)
2
Tryptophan Synthase Alpha Chain
(Gene symbol: trpA)
Molecule annotation
2
Tryptophan Synthase Beta Chain
(Gene symbol: trpB)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
2
MALONATE IONMALONATE ION
2
7
FORMIC ACIDFORMIC ACID
3
2
(2R,3S,4R)-3-(2'-fluoro[1,1'-biphenyl]-4-yl)-4-(hydroxymethyl)azetidine-2-carbonitrile(2R,3S,4R)-3-(2'-fluoro[1,1'-biphenyl]-4-yl)-4-(hydroxymethyl)azetidine-2-carbonitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303