5TCA: Complement Factor D inhibited with JH3

PDB ID: 5TCADownload
MMDB ID: 144204
PDB Deposition Date: 2016/9/14
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 3.15  Å
Source Organism:
Similar Structures:
Biological Unit for 5TCA: monomeric; determined by author and by software (PISA)
Molecular Components in 5TCA
Label Count Molecule
Protein (1 molecule)
1
Complement Factor D
(Gene symbol: CFD)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
1-(2-{(2S)-2-[(6-bromopyridin-2-yl)carbamoyl]-1,3-thiazolidin-3-yl}-2-oxoethyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide1-(2-{(2S)-2-[(6-bromopyridin-2-yl)carbamoyl]-1,3-thiazolidin-3-yl}-2-oxoethyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303