5TC6: Crystal structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase in complex with propylthio-immucillin-A

PDB ID: 5TC6Download
MMDB ID: 155542
PDB Deposition Date: 2016/9/14
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.48  Å
Source Organism:
Similar Structures:
Biological Unit for 5TC6: trimeric; determined by author and by software (PISA)
Molecular Components in 5TC6
Label Count Molecule
Proteins (3 molecules)
3
S-methyl-5'-thioadenosine Phosphorylase
(Gene symbol: MTAP)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
3
(2S,3S,4R,5S)-2-(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-[(propylsulfanyl)methyl]pyrrolidine-3,4-diol(2S,3S,4R,5S)-2-(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-[(propylsulfanyl)methyl]pyrrolidine-3,4-diol
2
3
PHOSPHATE IONPHOSPHATE ION
3
3
GLYCEROLGLYCEROL
4
1
SODIUM IONSODIUM ION
5
1
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303