5TBJ: Crystal structure of mouse CARM1 in complex with inhibitor LH1452

PDB ID: 5TBJDownload
MMDB ID: 154635
PDB Deposition Date: 2016/9/12
Updated in MMDB: 2017/10
Experimental Method:
x-ray diffraction
Resolution: 2.32  Å
Source Organism:
Similar Structures:
Biological Unit for 5TBJ: tetrameric; determined by software (PISA)
Molecular Components in 5TBJ
Label Count Molecule
Proteins (4 molecules)
4
Histone-arginine Methyltransferase Carm1
(Gene symbol: Carm1)
Molecule annotation
Chemicals and Non-standard biopolymers (21 molecules)
1
4
2-[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]ethyl-[[4-azanyl-1-(methoxymethyl)-2-oxidanylidene-pyrimidin-5-yl]methyl]azanium2-[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]ethyl-[[4-azanyl-1-(methoxymethyl)-2-oxidanylidene-pyrimidin-5-yl]methyl]azanium
2
4
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
3
11
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
1
1,2-DIMETHOXYETHANE1,2-DIMETHOXYETHANE
5
1
1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303