5TBI: Crystal structure of mouse CARM1 in complex with inhibitor LH1427

PDB ID: 5TBIDownload
MMDB ID: 154634
PDB Deposition Date: 2016/9/12
Updated in MMDB: 2017/10
Experimental Method:
x-ray diffraction
Resolution: 2.294  Å
Source Organism:
Similar Structures:
Biological Unit for 5TBI: tetrameric; determined by author and by software (PISA)
Molecular Components in 5TBI
Label Count Molecule
Proteins (4 molecules)
4
Histone-arginine Methyltransferase Carm1
(Gene symbol: Carm1)
Molecule annotation
Chemicals and Non-standard biopolymers (22 molecules)
1
17
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
2
5'-S-[(3S)-3-azaniumyl-3-carboxypropyl]-5'-thioadenosine5'-S-[(3S)-3-azaniumyl-3-carboxypropyl]-5'-thioadenosine
3
1
3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL
4
2
4-[2-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methylamino]ethylamino]-1-(methoxymethyl)pyrimidin-2-one4-[2-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methylamino]ethylamino]-1-(methoxymethyl)pyrimidin-2-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303