5TBC: PRECATALYTIC TERNARY COMPLEX OF HUMAN DNA POLYMERASE BETA WITH GAPPED DNA SUBSTRATE, INCORPORATED (-)3TC-MP AND AN ANOTHER INCOMING (-)3TC-TP NUCLEOTIDE

PDB ID: 5TBCDownload
MMDB ID: 146342
PDB Deposition Date: 2016/9/11
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.85  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 5TBC: tetrameric; determined by author and by software (PISA)
Molecular Components in 5TBC
Label Count Molecule
Protein (1 molecule)
1
DNA Polymerase Beta
Molecule annotation
Nucleotides(3 molecules)
1
5-mer Phosphorylated Downstream Primer
Molecule annotation
1
10- MER Primer
Molecule annotation
1
16- MER Template
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
1
Lamivudine TriphosphateLamivudine Triphosphate
2
6
SODIUM IONSODIUM ION
3
1
CHLORIDE IONCHLORIDE ION
4
1
[(2R,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl]methyl dihydrogen phosphate[(2R,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl]methyl dihydrogen phosphate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303