5T9U: Discovery of a Potent Cyclophilin Inhibitor (Compound 3) based on Structural Simplification of Sanglifehrin A

PDB ID: 5T9UDownload
MMDB ID: 146829
PDB Deposition Date: 2016/9/9
Updated in MMDB: 2017/04
Experimental Method:
x-ray diffraction
Resolution: 2.301  Å
Source Organism:
Similar Structures:
Biological Unit for 5T9U: monomeric; determined by author
Molecular Components in 5T9U
Label Count Molecule
Protein (1 molecule)
1
Peptidyl-prolyl Cis-trans Isomerase a
(Gene symbol: PPIA)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
3-[(3-hydroxyphenyl)methyl]-10,12-dimethoxy-9,11-dimethyl-6-(propan-2-yl)-19-oxa-1,4,7,25-tetraazabicyclo[19.3.1]pentacosa-13,15-diene-2,5,8,20-tetrone3-[(3-hydroxyphenyl)methyl]-10,12-dimethoxy-9,11-dimethyl-6-(propan-2-yl)-19-oxa-1,4,7,25-tetraazabicyclo[19.3.1]pentacosa-13,15-diene-2,5,8,20-tetrone
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303