5T8J: Synthesis And Biological Evaluation Of Novel Selective Androgen Receptor Modulators (sarms). Part Ii: Optimization Of 4-(pyrrolidin- 1-yl)benzonitrile Derivatives

PDB ID: 5T8JDownload
MMDB ID: 150139
PDB Deposition Date: 2016/9/7
Updated in MMDB: 2017/04
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 5T8J: monomeric; determined by author
Molecular Components in 5T8J
Label Count Molecule
Protein (1 molecule)
1
Androgen Receptor
(Gene symbol: AR)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
GlycerolGlycerol
2
1
2-Fluoro-4-[(2s,3s)-3-Hydroxy-2,3-Dimethylpyrrolidin-1-Yl]-3-Methylbenzonitrile2-Fluoro-4-[(2s,3s)-3-Hydroxy-2,3-Dimethylpyrrolidin-1-Yl]-3-Methylbenzonitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303