5T8E: Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs). Part II: Optimization of 4-(pyrrolidin-1-yl)benzonitrile derivatives

PDB ID: 5T8EDownload
MMDB ID: 150138
PDB Deposition Date: 2016/9/7
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.71  Å
Source Organism:
Similar Structures:
Biological Unit for 5T8E: monomeric; determined by author
Molecular Components in 5T8E
Label Count Molecule
Protein (1 molecule)
1
Androgen Receptor
(Gene symbol: AR)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
GLYCEROLGLYCEROL
2
1
2-chloro-4-[(2S,3S)-3-hydroxy-2-methylpyrrolidin-1-yl]-3-methylbenzonitrile2-chloro-4-[(2S,3S)-3-hydroxy-2-methylpyrrolidin-1-yl]-3-methylbenzonitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303