5T68: Crystal structure of Syk catalytic domain in complex with a furo[3,2-d]pyrimidine

PDB ID: 5T68Download
MMDB ID: 144455
PDB Deposition Date: 2016/9/1
Updated in MMDB: 2016/12
Experimental Method:
x-ray diffraction
Resolution: 2.93  Å
Source Organism:
Similar Structures:
Biological Unit for 5T68: dimeric; determined by author and by software (PISA)
Molecular Components in 5T68
Label Count Molecule
Proteins (2 molecules)
2
Tyrosine-protein Kinase SYK
(Gene symbol: SYK)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
N~4~-cyclopropyl-N~2~-(3-methyl-1H-indazol-6-yl)furo[3,2-d]pyrimidine-2,4-diamineN~4~-cyclopropyl-N~2~-(3-methyl-1H-indazol-6-yl)furo[3,2-d]pyrimidine-2,4-diamine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303