5T5T: AMPK bound to allosteric activator

PDB ID: 5T5TDownload
MMDB ID: 236498
PDB Deposition Date: 2016/8/31
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 3.46  Å
Source Organism:
Similar Structures:
Biological Unit for 5T5T: trimeric; determined by author and by software (PISA)
Molecular Components in 5T5T
Label Count Molecule
Proteins (3 molecules)
1
5'-amp-activated Protein Kinase Catalytic Subunit Alpha-1
(Gene symbol: Prkaa1)
Molecule annotation
1
5'-amp-activated Protein Kinase Subunit Beta-1
(Gene symbol: Prkab1)
Molecule annotation
1
5'-amp-activated Protein Kinase Subunit Gamma-1
(Gene symbol: Prkag1)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
1
STAUROSPORINESTAUROSPORINE
2
3
CHLORIDE IONCHLORIDE ION
3
2
SULFATE IONSULFATE ION
4
1
6-chloro-5-[6-(dimethylamino)-2-methoxypyridin-3-yl]-1H-indole-3-carboxylic acid6-chloro-5-[6-(dimethylamino)-2-methoxypyridin-3-yl]-1H-indole-3-carboxylic acid
5
2
ADENOSINE MONOPHOSPHATEADENOSINE MONOPHOSPHATE
6
1
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303