5T2H: Engineered variant of I-OnuI meganuclease targeting the Human TCRa gene; harbors 43 point mutations relative to wild-type I-OnuI

PDB ID: 5T2HDownload
MMDB ID: 150469
PDB Deposition Date: 2016/8/23
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.517  Å
Source Organism:
Similar Structures:
Biological Unit for 5T2H: trimeric; determined by author and by software (PISA)
Molecular Components in 5T2H
Label Count Molecule
Protein (1 molecule)
1
I-onui_e-htcra
Molecule annotation
Nucleotides(2 molecules)
1
DNA (26-mer)
Molecule annotation
1
DNA (26-mer)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303