5T0M: A histone H3K9M mutation traps histone methyltransferase Clr4 to prevent heterochromatin spreading

PDB ID: 5T0MDownload
MMDB ID: 143862
PDB Deposition Date: 2016/8/16
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.896  Å
Source Organism:
Similar Structures:
Biological Unit for 5T0M: dimeric; determined by author and by software (PISA)
Molecular Components in 5T0M
Label Count Molecule
Proteins (2 molecules)
1
Histone-lysine N-methyltransferase Ehmt2
(Gene symbol: EHMT2)
Molecule annotation
1
Thr-lys-gln-thr-ala-arg-nle-ser-thr-gly
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
4
ZINC IONZINC ION
2
1
S-ADENOSYLMETHIONINES-ADENOSYLMETHIONINE
3
1
S-ADENOSYL-L-HOMOCYSTEINES-ADENOSYL-L-HOMOCYSTEINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303