5T03: Crystal structure of heparan sulfate 6-O-sulfotransferase with bound PAP and glucuronic acid containing hexasaccharide substrate

PDB ID: 5T03Download
MMDB ID: 147019
PDB Deposition Date: 2016/8/15
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 5T03: monomeric; determined by author and by software (PISA)
Molecular Components in 5T03
Label Count Molecule
Protein (1 molecule)
1
Maltose Binding Protein - Heparan Sulfate 6-o-sulfotransferase Isoform 3 Fusion Protein
(Gene symbol: hs6st3b)
Molecule annotation
Chemicals and Non-standard biopolymers (41 molecules)
1
6
beta-D-glucopyranuronic acidbeta-D-glucopyranuronic acid
2
6
2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose
3
8
alpha-D-glucopyranosealpha-D-glucopyranose
4
1
ADENOSINE-3'-5'-DIPHOSPHATEADENOSINE-3'-5'-DIPHOSPHATE
5
1
P-NITROPHENOLP-NITROPHENOL
6
11
1,2-ETHANEDIOL1,2-ETHANEDIOL
7
3
CHLORIDE IONCHLORIDE ION
8
3
SODIUM IONSODIUM ION
9
2
L(+)-TARTARIC ACIDL(+)-TARTARIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303