5SYM: Cocrystal structure of the human acyl protein thioesterase 1 with an isoform-selective inhibitor, ML348

PDB ID: 5SYMDownload
MMDB ID: 144443
PDB Deposition Date: 2016/8/11
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.55  Å
Source Organism:
Similar Structures:
Biological Unit for 5SYM: monomeric; determined by author and by software (PISA)
Molecular Components in 5SYM
Label Count Molecule
Protein (1 molecule)
1
Acyl-protein Thioesterase 1
(Gene symbol: LYPLA1)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
1
N-[2-chloro-5-(trifluoromethyl)phenyl]-2-[4-(furan-2-carbonyl)piperazin-1-yl]acetamideN-[2-chloro-5-(trifluoromethyl)phenyl]-2-[4-(furan-2-carbonyl)piperazin-1-yl]acetamide
2
7
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
3
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303