5SY3: Structure-based Design Of A New Series Of N-piperidin-3-ylpyrimidine- 5-carboxamides As Renin Inhibitors

PDB ID: 5SY3Download
MMDB ID: 144596
PDB Deposition Date: 2016/8/10
Updated in MMDB: 2016/11
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 5SY3: monomeric; determined by author
Molecular Components in 5SY3
Label Count Molecule
Protein (1 molecule)
1
Renin
(Gene symbol: REN)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
1
N-Acetyl-D-GlucosamineN-Acetyl-D-Glucosamine
2
1
N-[(Furan-2-Yl)methyl]-5,6,7,8-Tetrahydro[1]benzothieno[2,3-D]pyrimidin-4-AmineN-[(Furan-2-Yl)methyl]-5,6,7,8-Tetrahydro[1]benzothieno[2,3-D]pyrimidin-4-Amine
3
6
Dimethyl SulfoxideDimethyl Sulfoxide
4
1
Di(Hydroxyethyl)etherDi(Hydroxyethyl)ether
5
1
Pentaethylene GlycolPentaethylene Glycol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303