5SX4: Crystal Structure of panitumumab in complex with epidermal growth factor receptor domain 3

PDB ID: 5SX4Download
MMDB ID: 143859
PDB Deposition Date: 2016/8/9
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 5SX4: trimeric; determined by author and by software (PISA)
Molecular Components in 5SX4
Label Count Molecule
Proteins (3 molecules)
1
Panitumumab FAB Light Chain
Molecule annotation
1
Panitumumab FAB Heavy Chain
Molecule annotation
1
Epidermal Growth Factor Receptor
(Gene symbol: EGFR)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
3
SULFATE IONSULFATE ION
2
1
GLYCEROLGLYCEROL
3
1
PENTAETHYLENE GLYCOLPENTAETHYLENE GLYCOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303