5SVR: Crystal structure of the ATP-gated human P2X3 ion channel bound to competitive antagonist A-317491

PDB ID: 5SVRDownload
MMDB ID: 143853
PDB Deposition Date: 2016/8/7
Updated in MMDB: 2017/10
Experimental Method:
x-ray diffraction
Resolution: 3.13  Å
Source Organism:
Similar Structures:
Biological Unit for 5SVR: trimeric; determined by author and by software (PISA)
Molecular Components in 5SVR
Label Count Molecule
Proteins (3 molecules)
3
P2X Purinoceptor 3
(Gene symbol: P2RX3)
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
6
N-ACETYL-D-GLUCOSAMINEN-ACETYL-D-GLUCOSAMINE
2
3
MAGNESIUM IONMAGNESIUM ION
3
1
SODIUM IONSODIUM ION
4
3
5-{[(3-phenoxyphenyl)methyl][(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl}benzene-1,2,4-tricarboxylic acid5-{[(3-phenoxyphenyl)methyl][(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl}benzene-1,2,4-tricarboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303