5SVM: Crystal structure of the ATP-gated human P2X3 ion channel bound to agonist 2-methylthio-ATP in the desensitized state

PDB ID: 5SVMDownload
MMDB ID: 143610
PDB Deposition Date: 2016/8/6
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 3.093  Å
Source Organism:
Similar Structures:
Biological Unit for 5SVM: trimeric; determined by author and by software (PISA)
Molecular Components in 5SVM
Label Count Molecule
Proteins (3 molecules)
3
P2X Purinoceptor 3
(Gene symbol: P2RX3)
Molecule annotation
Chemicals and Non-standard biopolymers (21 molecules)
1
9
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
3
2-(methylsulfanyl)adenosine 5'-(tetrahydrogen triphosphate)2-(methylsulfanyl)adenosine 5'-(tetrahydrogen triphosphate)
3
3
SODIUM IONSODIUM ION
4
3
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
5
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303